ESSENTIAL HYPERTENSION - APPROACH TO CLINICAL-DATA BY THE USE OF MODELS

被引：25

作者：

CHAU, NP ^{[1
]}

SAFAR, ME ^{[1
]}

LONDON, GM ^{[1
]}

WEISS, YA ^{[1
]}

机构：

[1] HOP BROUSSAIS,ARTERIAL HYPERTENS RES CTR,HEMODYNAM LAB,F-75674 PARIS 14,FRANCE

来源：

HYPERTENSION | 1979年 / 1卷 / 02期

关键词：

1967-Guyton-Coleman circulatory model; Clinical data; Essential hypertension; Function blocks; Model approach; Steady state;

D O I：

10.1161/01.HYP.1.2.86

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

A new approach, based on animal circulatory models, was proposed for the study of clinical data in hypertension. Clinical data were identified with steady states in models. From the study of models, possible impairments, susceptible to account for the observed deviations of steady states in men, were analyzed. To be specific, the 1967-Guyton-Coleman model was confronted with a set of data on essential hypertension. The approach afforded a physiological interpretation for statistical results performed on clinical data. © 1979 American Heart Association, Inc.

引用

页码：86 / 97

页数：12

共 10 条

[1] RELATIONSHIPS BETWEEN CARDIAC-OUTPUT, HEART-RATE AND BLOOD-VOLUME IN ESSENTIAL HYPERTENSION [J].

CHAU, NP ;

SAFAR, ME ;

WEISS, YA ;

LONDON, GM ;

SIMON, AC ;

MILLIEZ, PL .

CLINICAL SCIENCE AND MOLECULAR MEDICINE, 1978, 54 (02) :175-180

[2]

GUYTON AC, 1973, HYPERTENSION MECHANI, P25

[3]

GUYTON AC, 1969, CIRC RES S1, V24, P19

[4]

Guyton AC, 1973, CIRCULATORY PHYSL CA

[5]

Guyton AC, 1967, PHYSICAL BASES CIRCU, P179

[6] A CONFIDENCE INTERVAL ON THE ABSCISSA OF THE POINT OF INTERSECTION OF 2 FITTED LINEAR REGRESSIONS [J].

KASTENBAUM, MA .

BIOMETRICS, 1959, 15 (02) :323-324

[7] THE ESTIMATION OF THE PARAMETERS OF A LINEAR-REGRESSION SYSTEM OBEYING 2 SEPARATE REGIMES [J].

QUANDT, RE .

JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION, 1958, 53 (284) :873-880

[8] ESTIMATES FOR POINTS OF INTERSECTION OF 2 POLYNOMIAL REGRESSIONS [J].

ROBISON, DE .

JOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION, 1964, 59 (305) :214-+

[9] CONTROL OF CARDIAC-OUTPUT IN ESSENTIAL HYPERTENSION [J].

SAFAR, ME ;

CHAU, NP ;

WEISS, YA ;

LONDON, GM ;

MILLIEZ, PL .

AMERICAN JOURNAL OF CARDIOLOGY, 1976, 38 (03) :332-336

[10]

SCHWARTZ D, 1963, METHODES STATISTIQUE, P181

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