ONYCHOLYSIS OCCURRING DURING PUVA THERAPY

被引：14

作者：

MACKIE, RM

机构：

[1] University Department of Dermatology, Western Infirmary, Glasgow

来源：

CLINICAL AND EXPERIMENTAL DERMATOLOGY | 1979年 / 4卷 / 01期

关键词：

D O I：

10.1111/j.1365-2230.1979.tb01599.x

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

A patient with mycosis fungoides developed onycholysis of all finger nails during photo‐chemotherapy (PUVA). After shielding of the nails during UVA exposure normal regrowth was observed. Photo‐onycholysis has been recognized for many years as a possible sequel to cutaneous photosensitization complicating therapy with demethylchlortetracycline (Orentreich, Harber & Tromovitch, 1961; Samman, 1965) and also tetracycline hydrochloride and doxycycline (Frank, Cohen & Minkin, 1971). Despite the recent intense interest in the use of psoralens and UVA (PUVA) in the management of psoriasis and mycosis fungoides there are no recent reports of onycholysis complicating PUVA therapy. This report, therefore, records onycholysis occurring during the treatment of a patient with mycosis fungoides with PUVA. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

页码：111 / 113

页数：3

共 5 条

[1] Bettley F.R., Samman P., Photo‐onycholysis, Proceedings of the Royal Society of Medicine, 67, (1974)
[2] Frank S.B., Coehn H.J., Minkin W., Photo‐onycholysis due to cetracydinc hydrochloride and doxycycline, Archives of Dermatology, 103, pp. 520-521, (1971)
[3] Orentreich N., Harber L.C., Tsomovitch J.A., Photosensitivity and photo‐onycholysis due to demethylchlortetracycline, Archives of Dermatology, 83, pp. 730-737, (1961)
[4] Rau R.C., Flowers H.P., Barrett J.L., Photo‐onycholysis secondary to psoralen use, Archives of Dermatology, 114, (1978)
[5] Samman P.D., The Nails hi Disease, (1965)

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