EXPERIMENTAL TORTICOLLIS IN THE MARMOSET PRODUCED BY INJECTION OF 6-HYDROXYDOPAMINE INTO THE ASCENDING NIGROSTRIATAL PATHWAY

被引:18
作者
SAMBROOK, MA
CROSSMAN, AR
SLATER, P
机构
[1] UNIV MANCHESTER,DEPT PHYSIOL,MANCHESTER M13 9PT,LANCASHIRE,ENGLAND
[2] UNIV HOSP S MANCHESTER,DEPT NEUROL,MANCHESTER M20 8LR,ENGLAND
关键词
D O I
10.1016/0014-4886(79)90173-0
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Torticollis was observed in the marmoset following interruption of the ascending nigrostriatal dopaminergic pathway by injection of the specific catecholamine neurotoxin, 6-hydroxydopamine. It was possible to either accentuate or reverse the torticollis by manipulation of the relative dopamine activity of the two striata. The relationship between these findings and the etiology of torticollis in the primate is discussed. © 1979.
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页码:583 / 593
页数:11
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