IDENTIFICATION OF AN IGD-LIKE SURFACE-IMMUNOGLOBULIN ON RABBIT LYMPHOCYTES

被引：15

作者：

SIRE, J

COLLE, A

BOURGOIS, A

机构：

[1] Centre D'immunologie, Inserm, Cnrs, Marseille, Marseille‐Luminy

来源：

EUROPEAN JOURNAL OF IMMUNOLOGY | 1979年 / 9卷 / 01期

关键词：

D O I：

10.1002/eji.1830090104

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Rabbit immunoglobulin antigen receptor molecules were analyzed by electrophoresis in sodium dodecyl sulfate polyacrylamide gels. By sequential precipitation, using first anti‐μ and then anti‐L chain antisera, two different immunoglobulins of similar molecular weight could be demonstrated. After tryptic digestion, two fractions were identified: an IgMs and an Fab fragment, the latter appearing after a few minutes of incubation. Thus, as in man and in the mouse, two main immunoglobulin antigen receptors were found in the rabbit. One receptor on rabbit lymphocytes is an IgMs molecule, and the other is easily split in the hinge region like human and mouse IgD receptors. Copyright © 1979 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim

引用

页码：13 / 16

页数：4

共 24 条

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