POTENTIAL ANTI-MICROBIALS .2. SYNTHESIS AND INVITRO ANTIMICROBIAL EVALUATION OF SOME THIAZOLO[4,5-D]PYRIMIDINES

被引：32

作者：

BADAWEY, ESAM ^{[1
]}

RIDA, SM ^{[1
]}

HAZZA, AA ^{[1
]}

FAHMY, HTY ^{[1
]}

GOHAR, YM ^{[1
]}

机构：

[1] UNIV ALEXANDRIA,FAC SCI,DIV MICROBIOL,ALEXANDRIA,EGYPT

来源：

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY | 1993年 / 28卷 / 02期

关键词：

THIAZOLO[4,5-D]PYRIMIDINES; ANTIBACTERIAL; ANTIFUNGAL;

D O I：

10.1016/0223-5234(93)90002-V

中图分类号：

R914 [药物化学];

学科分类号：

100701 [药物化学];

摘要：

Some thiazolo[4,5-d]pyrimidines were prepared in order to investigate their antimicrobial activity. A significant inhibitory effect was recorded for many compounds against Staphylococcus aureus ATCC 25923 (3, 6, 9a; MIC = 10-20 mug/ml), Escherichia coli ATCC 25922 (3,5,9b, MIC = 40 mug/ml) and Candida albicans DSM 70443 (6, MIC = 50 mug/ml).

引用

页码：97 / 101

页数：5

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