IRON(III)-COPPER(II) AND MANGANESE(III)-COPPER(II) PROMOTED CYCLIZATIONS - A NEW STEREOSELECTIVE APPROACH TOWARDS ALPHA-METHYL SUBSTITUTED PENICILLIN DERIVATIVES

被引：10

作者：

CABRI, W

CANDIANI, I

BEDESCHI, A

机构：

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1994年 / 05期

关键词：

D O I：

10.1039/c39940000597

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The stereoselective synthesis of alpha-methyl substituted penicillin by Fe-III-Cu-II and Mn-III-Cu-II promoted cyclizations and and its relationship with the Baldwin's INPS (isopenicillin N synthase) mechanistic hypothesis on the biosynthesis of penicillin is described.

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页码：597 / 598

页数：2

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