A NOTE ON THE CALCULATION OF EXPECTED SURVIVAL, ILLUSTRATED BY THE SURVIVAL OF LIVER-TRANSPLANT PATIENTS

被引:39
作者
THOMSEN, BL
KEIDING, N
ALTMAN, DG
机构
[1] Statistical Research Unit, Faculty of Medicine, University of Copenhagen, Copenhagen, DK-2200
[2] Medical Statistics Laboratory, Imperial Cancer Research Fund, London, WC2A 3PX, P.O. Box 123, Lincoln's Inn Fields
关键词
D O I
10.1002/sim.4780100508
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Based on historical regression analyses of survival one may calculate expected survival curves for patients in a study group, based on their observed covariates. This note discusses this calculation and illustrates it on a comparison of the survival of a certain group of liver transplant patients to their prognosis under conservative treatment.
引用
收藏
页码:733 / 738
页数:6
相关论文
共 14 条
[1]  
Neuberger J., Altman D.G., Christensen E., Tygstrup N., Williams R., Use of a prognostic index in evaluation of liver transplantation for primary biliary cirrhosis, Transplantation, 4, pp. 713-716, (1986)
[2]  
Christensen E., Neuberger J., Crowe J., Altman D.G., Popper H., Portmann B., Doniach D., Ranek L., Tygstrup N., Williams R., Beneficial effect of azathioprine and prediction of prognosis in primary biliary cirrhosis. Final results of an international trial, Gastroenterology, 89, pp. 1084-1091, (1985)
[3]  
Makuch R.W., Adjusted survival curve estimation using covariates, Journal of Chronic Diseases, 3, pp. 437-443, (1982)
[4]  
Gail M.H., Byar D.B., Variance calculations for direct adjusted survival curves with applications to testing for no treatment effect, Biometrical Journal, 28, pp. 587-599, (1986)
[5]  
Markus B.H., Dickson E.R., Grambsch P.M., Fleming T.R., Mazzaferro V., Klintmalm G.B.G., Wiesner R.H., van Thiel D.H., Starzl T.E., Efficacy of liver transplantation in patients with primary biliary cirrhosis, The New England Journal of Medicine, 320, pp. 1709-1713, (1989)
[6]  
Bonsel G.J., Klompmaker I.J., van't Veer F., Habbema J.D.F., Slooff M.J.H., Use of prognostic models for assessment of value of liver transplantation in primary biliary cirrhosis, The Lancet, 335, pp. 493-497, (1990)
[7]  
Breslow N., Contribution to the discussion of D. R. Cox ‘Regression models and life tables, Journal of the Royal Statistical Society, Series B, 34, pp. 216-217, (1972)
[8]  
Hougaard P., Life table methods for heterogeneous populations: Distributions describing the heterogeneity, Biometrika, 71, pp. 75-83, (1984)
[9]  
Aalen O.O., Heterogeneity in survival analysis, Statistics in Medicine, 7, pp. 1121-1137, (1988)
[10]  
Ederer F., Axtell L.M., Cutler S.J., The relative survival rate: A statistical methodology, National Cancer Institute Monographs, 6, pp. 101-121, (1961)