REPEATED VITAL CAPACITY MEASUREMENTS AS PREDICTIVE PARAMETERS FOR MECHANICAL VENTILATION NEED AND WEANING SUCCESS IN THE GUILLAIN-BARRE-SYNDROME

被引:78
作者
CHEVROLET, JC [1 ]
DELEAMONT, P [1 ]
机构
[1] GENEVA UNIV HOSP,MED CLIN,GENEVA,SWITZERLAND
来源
AMERICAN REVIEW OF RESPIRATORY DISEASE | 1991年 / 144卷 / 04期
关键词
D O I
10.1164/ajrccm/144.4.814
中图分类号
R56 [呼吸系及胸部疾病];
学科分类号
摘要
In Guillain-Barre syndrome (GBS), respiratory failure is a life-threatening complication, and its occurrence may be difficult to predict. We studied prospectively 10 patients with GBS by serial measurements of pulmonary function and arterial blood gases from the time they were admitted to hospital. Five patients developed respiratory failure and had to be intubated, whereas the other five developed no ventilatory impairment. VC measurements were very useful in predicting respiratory failure several days before intubation. In patients who were eventually intubated, VC decreased during the 48 h preceding the occurrence of respiratory failure and intubation, which was required when VC was 15.2 +/- 3.7 ml/kg body weight (BW). In nonintubated patients, VC was stable and > 40 ml/kg BW. In addition, VC measurements allowed us to determine the beginning of the weaning procedure (no weaning trial could be performed successfully when VC was < 7 ml/kg BW), to rationally follow its course, and to choose the time for extubation, i.e., when VC was > 15 ml/kg BW.
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页码:814 / 818
页数:5
相关论文
共 29 条
[1]   VAGAL AFFERENTS, DIAPHRAGM FATIGUE, AND INSPIRATORY RESISTANCE IN ANESTHETIZED DOGS [J].
ADAMS, JM ;
FARKAS, GA ;
ROCHESTER, DF .
JOURNAL OF APPLIED PHYSIOLOGY, 1988, 64 (06) :2279-2286
[2]  
[Anonymous], 1978, Ann Neurol, V3, P565
[3]   ASSESSMENT OF HUMAN DIAPHRAGM STRENGTH AND ACTIVATION USING PHRENIC-NERVE STIMULATION [J].
BELLEMARE, F ;
BIGLANDRITCHIE, B .
RESPIRATION PHYSIOLOGY, 1984, 58 (03) :263-277
[4]   RESPIRATORY MUSCLE AND PULMONARY-FUNCTION IN POLYMYOSITIS AND OTHER PROXIMAL MYOPATHIES [J].
BRAUN, NMT ;
ARORA, NS ;
ROCHESTER, DF .
THORAX, 1983, 38 (08) :616-623
[5]   CLINICAL MANIFESTATIONS OF INSPIRATORY MUSCLE FATIGUE [J].
COHEN, CA ;
ZAGELBAUM, G ;
GROSS, D ;
ROUSSOS, C ;
MACKLEM, PT .
AMERICAN JOURNAL OF MEDICINE, 1982, 73 (03) :308-316
[6]   ANALYSIS OF LUNG-VOLUME RESTRICTION IN PATIENTS WITH RESPIRATORY MUSCLE WEAKNESS [J].
DETROYER, A ;
BORENSTEIN, S ;
CORDIER, R .
THORAX, 1980, 35 (08) :603-610
[7]   VITAL CAPACITY AS A MEASURE OF THE SPONTANEOUS BREATHING ABILITY IN POLIOMYELITIS [J].
FERRIS, BG ;
WARREN, A ;
BEALS, CA .
NEW ENGLAND JOURNAL OF MEDICINE, 1955, 252 (15) :618-622
[8]  
GIBSON GJ, 1977, AM REV RESPIR DIS, V115, P389
[9]  
HAPPER A, 1985, NEUROLOGY, V35, P1662
[10]  
HEWER R, 1968, Q J MED, V33, P479