A 2-COMPARTMENT PHOSPHATE-DOPED GEL PHANTOM FOR LOCALIZED SPECTROSCOPY

被引：4

作者：

HOWE, FA

GRIFFITHS, JR

机构：

[1] Department of Cellular and Molecular Sciences, Division of Biochemistry, St. George's Hospital Medical School, London, SW17 ORE, Cranmer Terrace

来源：

MAGNETIC RESONANCE IMAGING | 1992年 / 10卷 / 01期

关键词：

PHANTOM; PHOSPHORUS; LOCALIZED SPECTROSCOPY; ACRYLAMIDE GEL;

D O I：

10.1016/0730-725X(92)90381-9

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Acrylamide gel loaded with phosphate has been used in two compartment phantoms designed to assess localized spectroscopy techniques. A chemical shift difference of 2.3 ppm was produced by changing the pH from 6 to 8.9. The P-31 relaxation times were modified by doping the gels with paramagnetic ions. For a T1 of approximately 1 sec nickel doping gave a T2 of approximately 110 msec and manganese doping gave a T2 of approximately 8 msec. Gel phantoms are more robust than their liquid equivalent and are not prone to leakage. The construction of small compartments with very thin walls is possible, making this type of phantom suitable for small bore imaging/spectroscopy systems.

引用

页码：119 / 126

页数：8

共 17 条

[1]

Howe, Relaxation times in paramagnetically doped agarose gels as a function of temperature and ion concentration, Magn. Reson. Imaging, 6, pp. 263-270, (1988)

[2]

Mitchell, Kundel, Axel, Joseph, Agarose as a tissue equivalent phantom material for NMR imaging, Magn. Reson. Imaging, 4, pp. 263-266, (1986)

[3]

Walker, Lerski, Mathur De Vre, Binet, Yane, Preparation of agarose gels as reference substances for NMR relaxation time measurement, Magn. Reson. Imaging, 6, pp. 215-222, (1988)

[4]

Gore, Brown, Jianhui, Mueller, Good, NMR relaxation of water in hydrogel polymers: A model for tissue, Magn. Reson. Med., 9, pp. 325-332, (1989)

[5]

De Luca, Maraviglia, Mercurio, Biological tissue simulation and standard testing material for MRI, Magn. Reson. Med., 4, pp. 189-192, (1987)

[6]

Koenig, Brown, Relaxometry of tissue, NMR Spectroscopy of cells and Organisms, 2, (1989)

[7]

Howe, Griffiths, Phosphorus doped gel phantoms for localised NMR spectroscopy, Book of Abstracts. Amsterdam: Eighth Annual Meeting of the Society of Magnetic Resonance in Medicine, (1989)

[8]

Gadian, Nuclear Magnetic Resonance and Its Application to Living Systems, (1982)

[9]

Howe, Griffiths, The effects of inversion pulse width on ISIS localisation efficiency for short T<sub>2</sub> spins, Book of Abstracts. San Francisco: Tenth Annual Meeting of the Society of Magnetic Resonance in Medicine, (1991)

[10]

Ablett, Lillford, Baghdadi, Derbyshire, Nuclear magnetic resonance investigations of polysaccharide films, sols and gels, J. Colloid Interface Sci., 67, pp. 355-377, (1987)

← 1 2 →