MYELINATED NOCICEPTIVE AFFERENTS ACCOUNT FOR THE HYPERALGESIA THAT FOLLOWS A BURN TO THE HAND

被引：247

作者：

MEYER, RA ^{[1
]}

CAMPBELL, JN ^{[1
]}

机构：

[1] JOHNS HOPKINS UNIV, SCH MED, DEPT INFECT DIS, BALTIMORE, MD 21205 USA

来源：

SCIENCE | 1981年 / 213卷 / 4515期

关键词：

D O I：

10.1126/science.7280675

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Monkeys [Macaca fascicularis, M. mulatta] and human subjects were exposed to a series of thermal stimuli before and after a 53.degree. C, 30-s burn to the glabrous skin of the hand. The responses of C- and A-fiber nociceptive afferents in the monkeys and subjective responses by the humans were compared. The burn resulted in increased sensitivity of the A fibers, decreased sensitivity of the C fibers and increased pain sensibility (hyperalgesia) in the human subjects.

引用

页码：1527 / 1529

页数：3

共 14 条

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