KINETICS OF THE TRYPSINOGEN ACTIVATION BY ENTEROKINASE AND TRYPSIN

被引：22

作者：

VARON, R

HAVSTEEN, BH

VAZQUEZ, A

GARCIA, M

VALERO, E

CANOVAS, FG

机构：

[1] UNIV KIEL,INST BIOCHEM,W-2300 KIEL 1,GERMANY

[2] UNIV CASTILLA LA MANCHA,EU POLITECN ALBACETE,LA MANCHA,SPAIN

[3] UNIV MURCIA,DEPT BIOQUIM & BIOL MOLEC,MURCIA,SPAIN

来源：

JOURNAL OF THEORETICAL BIOLOGY | 1990年 / 145卷 / 01期

关键词：

D O I：

10.1016/S0022-5193(05)80538-7

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A global kinetic analysis of the mechanisms of the trypsinogen activation by enterokinase and trypsin is presented. The kinetic equations of both the transient-phase and the steady-state of these mechanisms are presented. In addition, we here derive the corresponding kinetic equations for the case in which the condition of rapid equilibrium prevails and we propose a kinetic data analysis. The significance of this approach to the treatment of other zymogen activation processes is discussed. © 1990 Academic Press Limited All rights reserved.

引用

页码：123 / 131

页数：9

共 18 条

[1] ON STRUCTURAL AND FUNCTIONAL ROLE OF CARBOXYLATES IN CHYMOTRYPSINOGEN A A COMPARISON WITH CHYMOTRYPSIN TRYPSINOGEN AND TRYPSIN [J].