SENSITIVITY OF SALMONELLA-TYPHIMURIUM YG1024 TO URINE MUTAGENICITY CAUSED BY CIGARETTE-SMOKING

被引：59

作者：

EINISTO, P ^{[1
]}

NOHMI, T ^{[1
]}

WATANABE, M ^{[1
]}

ISHIDATE, M ^{[1
]}

机构：

[1] NATL INST HYG SCI,DIV GENET & MUTAGENESIS,SETAGAYA KU,TOKYO 158,JAPAN

来源：

MUTATION RESEARCH | 1990年 / 245卷 / 02期

关键词：

Cigarette smoking; Salmonella typhimurium YG1024; Urine mutagenicity;

D O I：

10.1016/0165-7992(90)90005-5

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Salmonella typhimurium YG1024, an O-acetyltransferase-overproducing derivative of TA98, was found to be more sensitive in detecting mutagenicity in human urine caused by cigarette smoking, than the conventional strain TA98, in Ames test in the presence of S9 mix. YG1021, another derivative of TA98 with elevated nitroreductase levels, did not show increased sensitivity. These results suggest that the mutagenic compounds concentrated by Blue Rayon from smokers' urine are aromatic amino compounds. © 1990.

引用

页码：87 / 92

页数：6

共 14 条

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