FUNDAMENTAL ROLE OF HYALURONIDASE IN TISSUE - HYPOTHESIS ON THE PROTECTING AND RESTORING MECHANISMS OF THE CELLULAR-UNIT WITH THEIR CLINICAL CONSEQUENCES

被引:12
作者
BOK, SW
机构
关键词
cellular unit; cell metabolism; hyaluronidase; protection; restoration;
D O I
10.1016/0306-9877(79)90002-1
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
The interstitial ground substance plays an essential role in the physiological processes of the capillary and the cell. Together they form a fundamental unit of function in which the cell is the most important part. Therefore the fundamental unit is called: THE CELLULAR UNIT. It is proposed central role and that this enzyme is indispensible for normal healthy cells as well as for the reactive mechanism in critical situations. The reactive mechanisms can be divided into a local reactive mechanism and a general reactive mechanism. The local reactive mechanism has a function of RESTORATION. The general reactive mechanism is especially for PROTECTION AGAINST ISCHAEMIA and REDISTRIBUTION OF TOTAL BODY NUTRIENTS in order to stimulate the restoration. These two mechanisms may have important clinical consequences. © 1979.
引用
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页码:1183 / 1200
页数:18
相关论文
共 39 条
[1]  
BANGA I, 1957, CONNECT TISSUE, P254
[3]  
BLUMBERG BS, 1958, CIBA F S CHEM BIOL M, P22
[4]  
BOLLET AJ, 1963, J BIOL CHEM, V238, P3522
[5]   UPTAKE OF SULPHATES IN MUCOPOLYSACCHARIDES ESTERIFIED WITH SULPHURIC ACID IN THE SKIN OF ADULT RATS AFTER INTRAPERITONEAL INJECTION OF S-35-LABELLED SODIUM SULPHATE [J].
BOSTROM, H ;
GARDELL, S .
ACTA CHEMICA SCANDINAVICA, 1953, 7 (01) :216-222
[6]  
CAMERON E, 1966, HYALURONIDASE CANCER, P32
[7]   SEROMUCOID GROUND SUBSTANCE + HYPOTHYROIDISM [J].
CAMPBELL, A ;
MOLLISON, A ;
CAMERON, E .
JOURNAL OF CLINICAL PATHOLOGY, 1964, 17 (06) :655-&
[8]   INTERCELLULAR CEMENT AND CAPILLARY PERMEABILITY [J].
CHAMBERS, R ;
ZWEIFACH, BW .
PHYSIOLOGICAL REVIEWS, 1947, 27 (03) :436-463
[9]  
CHRISTIE R, 1965, J MOND PHARM, V8, P5
[10]  
DEROBERTIS EDP, 1965, CELLBIOLOGY, P361