SYNTHESIS OF UNSATURATED TRICYCLIC LACTONES - THE COUPLING OF THE ENOL TRIFLATE OF BETA-KETO LACTONES WITH LITHIUM DIMETHYLCUPRATE

被引：8

作者：

BACIGALUPPO, JA ^{[1
]}

COLOMBO, MI ^{[1
]}

ZINCZUK, J ^{[1
]}

RUVEDA, EA ^{[1
]}

机构：

[1] FAC CIENCIAS BIOQUIM & FARMACEUT,UNR,CONICET,INST QUIM ORGAN SINTESIS,CASILLA CORREO 991,RA-2000 ROSARIO,ARGENTINA

来源：

SYNTHETIC COMMUNICATIONS | 1992年 / 22卷 / 13期

关键词：

D O I：

10.1080/00397919208021329

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The anions of selected beta-keto lactones were transformed into their corresponding enol triflates. These enol triflates were coupled with lithium dimethylcuprate to afford tricyclic unsaturated lactones, key intermediates for the synthesis of the biologically important natural product forskolin.

引用

页码：1973 / 1984

页数：12

共 20 条

[1] SYNTHESIS OF THE 3 ISOMERIC COMPONENTS OF SAN-JOSE SCALE PHEROMONE
ALDERDICE, M
SPINO, C
WEILER, L
[J]. TETRAHEDRON LETTERS, 1984, 25 (16) : 1643 - 1646
[2] ALDERDICE M, 1984, ORG SYNTH, V62, P14
[3] SYNTHETIC ROUTES TO FORSKOLIN
COLOMBO, MI
ZINCZUK, J
RUVEDA, EA
[J]. TETRAHEDRON, 1992, 48 (06) : 963 - 1037
[4] SYNTHESIS OF THE ZIEGLER KEY INTERMEDIATE AND RELATED PRECURSORS FOR THE SYNTHESIS OF FORSKOLIN AND ERIGEROL
COLOMBO, MI
ZINCZUK, J
BACIGALUPPO, JA
SOMOZA, C
RUVEDA, EA
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1990, 55 (21) : 5631 - 5639
[5] TOTAL SYNTHESIS OF (+/-)-FORSKOLIN
COREY, EJ
JARDINE, PD
ROHLOFF, JC
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1988, 110 (11) : 3672 - 3673
[6] STEREOCONTROLLED SYNTHESES AND BIOLOGICAL PROFILES OF (+/-)-6,7-DIDEOXYFORSKOLIN AND ITS 13-EPIMER
HASHIMOTO, S
BAN, M
YANAGIYA, Y
SAKATA, S
IKEGAMI, S
[J]. TETRAHEDRON LETTERS, 1991, 32 (32) : 4027 - 4030
[7] A STEREOCONTROLLED SYNTHESIS OF (+/-)-1,6,7-TRIDEOXYFORSKOLIN
HASHIMOTO, S
SONEGAWA, M
SAKATA, S
IKEGAMI, S
[J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1987, (01) : 24 - 25
[8] HENDRICK.JB, 1973, TETRAHEDRON LETT, P4607
[9] TOTAL SYNTHESIS OF (+/-)-JOLKINOLIDE A, B, AND E UTILIZING A NEW MILD ESTERIFICATION FOLLOWED BY INTRAMOLECULAR WITTIG HORNER REACTION
KATSUMURA, S
KIMURA, A
ISOE, S
[J]. TETRAHEDRON, 1989, 45 (05) : 1337 - 1346
[10] SYNTHESIS OF A POTENTIAL FORSKOLIN-A-B RING PRECURSOR BY TANDEM MICHAEL-ALDOL REACTIONS
KOFT, ER
KOTNIS, AS
BROADBENT, TA
[J]. TETRAHEDRON LETTERS, 1987, 28 (25) : 2799 - 2800

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