TROPHIC ACTION OF EPIDERMAL GROWTH-FACTOR ON HUMAN DUODENAL MUCOSA CULTURED INVITRO

被引：21

作者：

CHALLACOMBE, DN

WHEELER, EE

机构：

[1] Somerset Children's Research Unit, Musgrove Park Hospital, Taunton

来源：

GUT | 1991年 / 32卷 / 09期

关键词：

D O I：

10.1136/gut.32.9.991

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

The action of epidermal growth factor on the human duodenal mucosa has been studied by estimating the crypt cell production rate in cultured explants, using a stathmokinetic technique with crypt microdissection. The addition of epidermal growth factor (400 ng/ml) to paired explants from five patients caused an almost fivefold increase in the crypt cell production rate, showing that epidermal growth factor has a trophic action on the human duodenal mucosa in vitro.

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页码：991 / 993

页数：3

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