BEYOND SPECIFICITY - EFFECTS OF SEROTONIN AND SEROTONERGIC TREATMENTS ON PSYCHOBIOLOGICAL DYSFUNCTION

被引:30
作者
DUBOVSKY, SL
THOMAS, M
机构
[1] UNIV COLORADO, SCH MED, DEPT PSYCHIAT, DENVER, CO 80262 USA
[2] UNIV COLORADO, SCH MED, DEPT MED, DENVER, CO 80262 USA
关键词
D O I
10.1016/0022-3999(94)00043-5
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Serotonin is a ubiquitous neurotransmitter with widespread projections that provide for the involvement of serotonin in the regulation of many biological and psychological functions. A variety of serotonin receptor subtypes exist that mediate overlapping psychobiological functions and that are targets for a new generation of medications. Although these new generation medications appear to possess great biochemical specificity, their actions extend to many psychiatric disorders, reflecting the many interactions of serotonergic subsystems.
引用
收藏
页码:429 / 444
页数:16
相关论文
共 103 条
[1]   THE ANTIDEPRESSANT EFFECTS OF 5-HT UPTAKE INHIBITORS [J].
ABERGWISTEDT, A .
BRITISH JOURNAL OF PSYCHIATRY, 1989, 155 :32-40
[2]  
AGHAJANIAN GK, 1992, CENTRAL SEROTONIN RE, P39
[3]   GEPIRONE, A SELECTIVE SEROTONIN (5HT(1A)) PARTIAL AGONIST IN THE TREATMENT OF MAJOR DEPRESSION [J].
AMSTERDAM, JD .
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 1992, 16 (03) :271-280
[4]  
Andersen B, 1990, J AFFECT DISORDERS, V18, P289
[5]  
ANNSEU ON, 1991, BRIT MED J, V303, P760
[6]  
APTER A, 1990, ROLE SEROTONIN PSYCH, P215
[7]  
APTER A, 1990, ROLE SEROTONIN PSYCH, P284
[8]  
ASBERG M, 1982, PSYCHOPHARMACOL BULL, V18, P13
[9]  
AYD FJ, 1990, INT DRUG THERAPY NEW, V25, P17
[10]  
BARNAS C, 1991, Fortschritte der Neurologie Psychiatrie, V59, P36, DOI 10.1055/s-2007-1000733