XERODERMA-PIGMENTOSUM AND NUCLEOTIDE EXCISION-REPAIR OF DNA

被引:95
作者
TANAKA, K [1 ]
WOOD, RD [1 ]
机构
[1] IMPERIAL CANC RES FUND,CLARE HALL LABS,S MIMMS EN6 3LD,HERTS,ENGLAND
关键词
D O I
10.1016/0968-0004(94)90040-X
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Nucleotide excision repair is a versatile strategy for removing DNA damage from the genome. Tremendous progress in understanding this process has been made in the last few years, and the field continues to develop rapidly. Exciting connections have emerged between nucleotide excision repair, transcription, and DNA replication, but many mysteries remain concerning the biochemical details of the mechanism, the connection with several human inherited syndromes, and the role of DNA repair in preventing cancer.
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页码:83 / 86
页数:4
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