GAS CHROMATOGRAPHIC-MASS SPECTROMETRIC EVIDENCE FOR THE IDENTIFICATION OF 1,2,3,4-TETRAHYDRO-BETA-CARBOLINE AS AN INVIVO CONSTITUENT OF RAT-BRAIN

被引：64

作者：

BARKER, SA ^{[1
]}

HARRISON, RE ^{[1
]}

BROWN, GB ^{[1
]}

CHRISTIAN, ST ^{[1
]}

机构：

[1] UNIV ALABAMA,DEPT PSYCHIAT,BIRMINGHAM,AL 35294

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1979年 / 87卷 / 01期

关键词：

D O I：

10.1016/0006-291X(79)91659-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Based on gas chromatographic/mass spectrometric data, obtained using the method of selected ion monitoring, the compound 1,2,3,4-tetrahydro-β-carboline has been tentatively identified as an invivo constituent of rat brain. © 1979.

引用

页码：146 / 154

页数：9

共 31 条

[1]

BARCHAS JD, 1974, ARCH GEN PSYCHIAT, V31, P862

[2]

BARKER SA, 1978, THESIS U ALA BHAM

[3] IDENTIFICATION AND SEPARATION OF INDOLEALKYLAMINES BY GAS-LIQUID-CHROMATOGRAPHIC ANALYSIS OF THEIR HEPTAFLUOROBUTYRYL DERIVATIVES [J].

BENINGTON, F ;

CHRISTIAN, ST ;

MORIN, RD .

JOURNAL OF CHROMATOGRAPHY, 1975, 106 (02) :435-439

[4]

Boulton A A, 1970, J Chromatogr, V48, P322, DOI 10.1016/S0021-9673(01)85561-8

[5] INHIBITION BY BETA-CARBOLINES OF MONOAMINE UPTAKE INTO A SYNAPTOSOMAL PREPARATION - STRUCTURE-ACTIVITY-RELATIONSHIPS [J].

BUCKHOLTZ, NS ;

BOGGAN, WO .

LIFE SCIENCES, 1977, 20 (12) :2093-2099

[6] MONOAMINE-OXIDASE INHIBITION IN BRAIN AND LIVER PRODUCED BY BETA-CARBOLINES - STRUCTURE-ACTIVITY-RELATIONSHIPS AND SUBSTRATE-SPECIFICITY [J].

BUCKHOLTZ, NS ;

BOGGAN, WO .

BIOCHEMICAL PHARMACOLOGY, 1977, 26 (21) :1991-1996

[7] METHYLENETETRAHYDROFOLATE REDUCTASE IN RAT CENTRAL NERVOUS-SYSTEM - INTRACELLULAR AND REGIONAL DISTRIBUTION [J].

BURTON, EG ;

SALLACH, HJ .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1975, 166 (02) :483-494

[8] FURTHER INSIGHT INTO METABOLISM OF CERTAIN BETA-CARBOLINES [J].

DAJANI, RM ;

SAHEB, SE .

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1973, 215 (APR30) :120-123

[9]

ELLIOTT GR, 1977, NEUROREGULATORS PSYC, P220

[10] Synthesis of tetrahydro-harman-derivatives on the physiologiacal conditions, I. (temporary) Announcement. [J].

Hahn, G ;

Ludewig, H .

BERICHTE DER DEUTSCHEN CHEMISCHEN GESELLSCHAFT, 1934, 67 :2031-2035

← 1 2 3 4 →