DOES OBSTRUCTIVE-JAUNDICE ADVERSELY AFFECT WOUND-HEALING

被引：17

作者：

GREANEY, MG

VANNOORT, R

SMYTHE, A

IRVIN, TT

机构：

[1] UNIV SHEFFIELD,HALLAMSHIRE HOSP,DEPT SURG,SHEFFIELD S10 2TN,S YORKSHIRE,ENGLAND

[2] UNIV SHEFFIELD,HALLAMSHIRE HOSP,DEPT MED PHYS,SHEFFIELD S10 2TN,S YORKSHIRE,ENGLAND

[3] ROYAL DEVON & EXETER HOSP,EXETER,DEVONSHIRE,ENGLAND

来源：

BRITISH JOURNAL OF SURGERY | 1979年 / 66卷 / 07期

关键词：

D O I：

10.1002/bjs.1800660708

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

The effect of obstructive jaundice on wound healing has been investigated in an experimental study of abdominal wounds in rats following ligation and division of the common bile duct. Animals were jaundiced for 2 weeks before a second operation at which the abdominal wounds were made. The wounds in jaundiced and control animals showed no significant differences in mechanical strength during a 21‐day period of study but there was a significant delay in the accumulation of collagen in the wounds of jaundiced animals. The findings suggest that the biochemical changes in the wounds of jaundiced animals did not interfere with wound repair and cast doubt on the thesis that jaundice has an adverse effect on wound healing. Copyright © 1979 British Journal of Surgery Society Ltd.

引用

页码：478 / 481

页数：4