ACUTE TUBULAR-NECROSIS IN KIDNEY-TRANSPLANT PATIENTS TREATED WITH ENALAPRIL

被引：13

作者：

GARCIA, TMP ^{[1
]}

DACOSTA, JAC ^{[1
]}

COSTA, RS ^{[1
]}

FERRAZ, AS ^{[1
]}

机构：

[1] UNIV SAO PAULO,HOSP CLIN,FAC MED RIBEIRAO PRETO,RENAL TRANSPLANTAT UNIT,BR-14048900 RIBEIRAO PRET,SP,BRAZIL

来源：

RENAL FAILURE | 1994年 / 16卷 / 03期

关键词：

ANGIOTENSIN-CONVERTING ENZYME INHIBITOR; CYCLOSPORINE; RENAL FAILURE; TRANSPLANTATION;

D O I：

10.3109/08860229409044882

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

We report two cases of acute renal failure in renal transplant patients using cyclosporine-A (CsA) after the introduction of angiotensin-converting enzyme inhibitor (ACEI) to control arterial hypertension. They had no renal artery stenosis or acute rejection. Both patients presented severe acute tubular necrosis (ATN), which subsided after discontinuation of the ACEI. Synergistic toxic effect of ACEI and CsA on the renal tubules might explain ATN in these two cases.

引用

页码：419 / 423

页数：5

共 9 条

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[2]

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