1-ALPHA,25-DIHYDROXYVITAMIN D-3 HYBRID ANALOGS WITH STRUCTURAL-CHANGES AT BOTH THE A-RING AND THE C,D-RING SIDE-CHAIN

被引：25

作者：

POSNER, GH

WHITE, MC

DOLAN, P

KENSLER, TW

YUKIHIRO, S

GUGGINO, SE

机构：

[1] JOHNS HOPKINS UNIV,SCH HYG & PUBL HLTH,DIV TOXICOL SCI,BALTIMORE,MD 21218

[2] JOHNS HOPKINS UNIV,SCH HYG & PUBL HLTH,ENVIRONM HLTH SCI CTR,DEPT ENVIRONM HLTH SCI,BALTIMORE,MD 21218

[3] JOHNS HOPKINS UNIV,SCH MED,DEPT MED,BALTIMORE,MD 21218

[4] JOHNS HOPKINS UNIV,SCH MED,DEPT NEUROSCI,BALTIMORE,MD 21218

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1994年 / 4卷 / 24期

关键词：

D O I：

10.1016/S0960-894X(01)80840-4

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Calcitriol analogs 5, designed to combine two remote structural changes each of which separately produces a sharply different biological profile, have biological activities that are a blending of the effects of each structural change.

引用

页码：2919 / 2924

页数：6

共 30 条

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