LONG-TERM PRESERVATION AND INDUCTION OF DRUG-METABOLIZING-ENZYMES IN COCULTURED RAT HEPATOCYTES

被引：2

作者：

AKRAWI, M

ROGIERS, V

VERCRUYSSE, A

PHILLIPS, IR

SHEPHARD, EA

机构：

[1] FREE UNIV BRUSSELS,DEPT TOXICOL,B-1090 BRUSSELS,BELGIUM

[2] UNIV LONDON QUEEN MARY & WESTFIELD COLL,DEPT BIOCHEM,LONDON E1 4NS,ENGLAND

来源：

BIOCHEMICAL SOCIETY TRANSACTIONS | 1994年 / 22卷 / 02期

关键词：

D O I：

10.1042/bst022124s

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：S124 / S124

页数：1

共 10 条

[1] MAINTENANCE AND INDUCTION IN COCULTURED RAT HEPATOCYTES OF COMPONENTS OF THE CYTOCHROME-P450-MEDIATED MONOOXYGENASE [J].

AKRAWI, M ;

ROGIERS, V ;

VANDENBERGHE, Y ;

PALMER, CNA ;

VERCRUYSSE, A ;

SHEPHARD, EA ;

PHILLIPS, IR .

BIOCHEMICAL PHARMACOLOGY, 1993, 45 (08) :1583-1591

[2] EFFECTS OF PHENOBARBITAL AND VALPROATE ON THE EXPRESSION OF CYTOCHROMES P-450 IN COCULTURED RAT HEPATOCYTES [J].

AKRAWI, M ;

SHEPHARD, EA ;

PHILLIPS, IR ;

VERCRUYSSE, A ;

ROGIERS, V .

TOXICOLOGY IN VITRO, 1993, 7 (04) :477-480

[3] METABOLIC-ACTIVATION OF VALPROIC ACID AND DRUG-MEDIATED HEPATOTOXICITY - ROLE OF THE TERMINAL OLEFIN, 2-NORMAL-PROPYL-4-PENTENOIC ACID [J].

BAILLIE, TA .

CHEMICAL RESEARCH IN TOXICOLOGY, 1988, 1 (04) :195-199

[4] PROLONGED MAINTENANCE OF ACTIVE CYTOCHROME-P-450 IN ADULT-RAT HEPATOCYTES CO-CULTURED WITH ANOTHER LIVER-CELL TYPE [J].

BEGUE, JM ;

GUGUENGUILLOUZO, C ;

PASDELOUP, N ;

GUILLOUZO, A .

HEPATOLOGY, 1984, 4 (05) :839-842

[5]

BISSELL DM, 1980, GASTROENTEROLOGY, V72, P1232

[6] MICROSOMAL LAURIC ACID HYDROXYLASE-ACTIVITIES AFTER TREATMENT OF RATS WITH 3 CLASSICAL CYTOCHROME-P450 INDUCERS AND PEROXISOME PROLIFERATING COMPOUNDS [J].

DIRVEN, HAAM ;

VANDENBROEK, PHH ;

PETERS, JGP ;

NOORDHOEK, J ;

JONGENEELEN, FJ .

BIOCHEMICAL PHARMACOLOGY, 1992, 43 (12) :2621-2629

[7] ALTERATIONS IN THE RENAL EXCRETION OF VALPROATE AND ITS METABOLITES AFTER CHRONIC TREATMENT [J].

FISHER, JE ;

NAU, H ;

LOSCHER, W .

EPILEPSIA, 1991, 32 (01) :146-150

[8] REGULATION OF GENE-EXPRESSION IN ADULT-RAT HEPATOCYTES CULTURED ON A BASEMENT-MEMBRANE MATRIX [J].

SCHUETZ, EG ;

LI, D ;

OMIECINSKI, CJ ;

MULLEREBERHARD, U ;

KLEINMAN, HK ;

ELSWICK, B ;

GUZELIAN, PS .

JOURNAL OF CELLULAR PHYSIOLOGY, 1988, 134 (03) :309-323

[9] PHENOBARBITAL INDUCTION OF CYTOCHROMES-P-450 - HIGH-LEVEL LONG-TERM RESPONSIVENESS OF PRIMARY RAT HEPATOCYTE CULTURES TO DRUG INDUCTION, AND GLUCOCORTICOID DEPENDENCE OF THE PHENOBARBITAL RESPONSE [J].

WAXMAN, DJ ;

MORRISSEY, JJ ;

NAIK, S ;

JAUREGUI, HO .

BIOCHEMICAL JOURNAL, 1990, 271 (01) :113-119

[10]

ZIMMERMAN HJ, 1982, HEPATOLOGY, V2, P591

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