EXCRETION AND BIOTRANSFORMATION OF ASTEMIZOLE IN RATS, GUINEA-PIGS, DOGS, AND MAN

被引：22

作者：

MEULDERMANS, W ^{[1
]}

HENDRICKX, J ^{[1
]}

LAUWERS, W ^{[1
]}

HURKMANS, R ^{[1
]}

SWYSEN, E ^{[1
]}

HEYKANTS, J ^{[1
]}

机构：

[1] JANSSEN PHARMACEUT,RES LABS,DEPT ANALYT RES,B-2340 BEERSE,BELGIUM

来源：

关键词：

D O I：

10.1002/ddr.430080106

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：37 / 51

页数：15

共 7 条

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[2] MEULDERMANS W, 1981, European Journal of Drug Metabolism and Pharmacokinetics, V6, P49
[3] PHARMACOKINETICS AND TISSUE DISTRIBUTION OF ASTEMIZOLE IN THE DOG
MICHIELS, M
VANPEER, A
WOESTENBORGHS, R
HEYKANTS, J
[J]. DRUG DEVELOPMENT RESEARCH, 1986, 8 (1-4) : 53 - 62
[4] ASTEMIZOLE - A REVIEW OF ITS PHARMACODYNAMIC PROPERTIES AND THERAPEUTIC EFFICACY
RICHARDS, DM
BROGDEN, RN
HEEL, RC
SPEIGHT, TM
AVERY, GS
[J]. DRUGS, 1984, 28 (01) : 38 - 61
[5] Smith RL, 1973, EXCRETORY FUNCTION B, P76
[6] TESTA B, 1976, DRUG METABOLISM CHEM, P202
[7] SYNTHESIS OF H-3-LABELED AND C-14-LABELED ASTEMIZOLE (R-43-512)
THIJSSEN, JBA
KNAEPS, AG
HEYKANTS, JJP
[J]. JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 1983, 20 (07) : 861 - 868