ANNOMONTACIN - NEW CYTOTOXIC ACETOGENIN GAMMA-LACTONE MONOTETRAHYDROFURAN ISOLATED FROM ANNONA-MONTANA

被引：41

作者：

JOSSANG, A

DUBAELE, B

CAVE, A

BARTOLI, MH

BERIEL, H

机构：

[1] UNIV PARIS SUD,FAC PHARM,PHARMACOG LAB,CNRS,URA 496,F-92296 CHATENAY MALABRY,FRANCE

[2] FAC PHARM GRENOBLE,PHYSIOL PHARMACOL LAB,F-38706 LA TRONCHE,FRANCE

来源：

JOURNAL OF NATURAL PRODUCTS | 1991年 / 54卷 / 04期

关键词：

D O I：

10.1021/np50076a007

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The structure of annomontacin [1], a novel monotetrahydrofuran fatty acid gamma-lactone (acetogenin) isolated from the seeds of Annona montana, was determined by spectral analysis. The cytotoxicities in vitro of annomontacin [1], annonacinone [2], and annonacin were measured against murine leukemia L1210, human breast adenocarcinoma MDA-MB231, and human breast carcinoma MCF7 cell lines and compared with adriamycin.

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页码：967 / 971

页数：5

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