PROSTAGLANDINS - A ROLE IN ADHESION FORMATION An Experimental Study

被引：16

作者：

Golan, A. ^{[1
,3
]}

Stolik, O. ^{[2
]}

Wexler, S. ^{[2
]}

Langer, R. ^{[1
,3
]}

Ber, A. ^{[2
]}

David, M. P. ^{[2
]}

机构：

[1] Assaf Harofeh Med Ctr, Dept Obstet & Gynecol, IL-70300 Zerifin, Israel

[2] Serlin Matern Hosp, Dept Obstet & Gynecol, Tel Aviv, Israel

[3] Tel Aviv Univ, Sch Med, Tel Aviv, Israel

来源：

ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA | 1990年 / 69卷 / 04期

关键词：

prostaglandins; adhesions; experiment;

D O I：

10.3109/00016349009036158

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

The effect of intraperitoneal application of prostaglandins F(2Alpha) and E, on adhesion formation was studied in the rat after traumatizing to the uterine serosa. Prostaglandins applied locally were found to increase intraperitoneal adhesion formation at the injury site, in comparison with controls. The effect of intraperitoneal application of prostaglandins F(2Alpha) and E(2) on fibroblastic proliferation was examined in vitro, by fibroblastic cell culture of rat kidney. human kidney and human prepuce. No direct effect of prostaglandins on fibroblast proliferation could be demonstated. It is concluded that prostaglandins play an important role in the process of adhesion formation. This effect in not related to fibrobalast proliferation.

引用

页码：339 / 341

页数：3

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