CHARACTERIZATION OF A DICARBOXYLIC ACID-PRODUCING MUTANT OF THE YEAST CANDIDA-TROPICALIS

被引：11

作者：

ATOMI, H

YU, C

HARA, A

MATSUI, T

NAITO, N

KAMASAWA, N

OSUMI, M

UEDA, M

TANAKA, A

机构：

[1] KYOTO UNIV,FAC ENGN,DEPT SYNTHET CHEM & BIOL CHEM,APPL BIOL CHEM LAB,SAKYO KU,KYOTO 60601,JAPAN

[2] JAPAN ENERGY CO,PHARMACEUT & BIOTECHNOL LAB,TODA,SAITAMA 335,JAPAN

[3] JAPAN WOMENS UNIV,FAC SCI,DEPT CHEM & BIOL SCI,BUNKYO KU,TOKYO 112,JAPAN

来源：

JOURNAL OF FERMENTATION AND BIOENGINEERING | 1994年 / 77卷 / 02期

关键词：

D O I：

10.1016/0922-338X(94)90326-3

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

A comparative study was carried out on the biosynthesis of peroxisomal enzymes in the n-alkane-assimilating yeast Candida tropicalis 1098 and its dicarboxylic acid-producing mutant M2030. The mutant strain showed a drastic decrease in protein levels in acyl-CoA oxidase and 3-ketoacyl-CoA thiolase, constituting the yeast peroxisomal beta-oxidation system, in comparison with those of the wild-type strain. Interestingly, the development of peroxisomes was scarcely observed in the mutant strain.

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页码：205 / 207

页数：3

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