EFFICACY OF PINDOLOL FOR TREATMENT OF VASOVAGAL SYNCOPE

被引：25

作者：

COHEN, MB ^{[1
]}

SNOW, JS ^{[1
]}

GRASSO, V ^{[1
]}

LEHNERT, L ^{[1
]}

GOLDNER, BG ^{[1
]}

JADONATH, RL ^{[1
]}

COHEN, TJ ^{[1
]}

机构：

[1] N SHORE UNIV HOSP,CORNELL UNIV MED COLL,DEPT MED,DIV CARDIOL,ELECTROPHYSIOL SECT,MANHASSET,NY 11030

来源：

AMERICAN HEART JOURNAL | 1995年 / 130卷 / 04期

关键词：

D O I：

10.1016/0002-8703(95)90078-0

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The purpose of this study was to evaluate the efficacy, safety, and tolerance of pindolol as initial therapy for vasovagal syncope. Head-up tilt table testing (HUT) was performed on 192 patients for syncope or near-syncope of unknown cause. Forty-four (23%) patients had a positive HUT for vasovagal syncope, and 28 (64%) received oral pindolol as initial therapy. Three patients were lost to follow-up; of the remaining 25 patients (mean age 60 +/- 22 years), 15 were women, 14 had syncope, and 11 had near-syncope. At 14 +/- 6 months' follow-up, 16 (64%) patients were without recurrence or side effects from pindolol. Of the 9 patients who stopped taking pindolol, 3 were switched to another regimen for recurrent symptoms, 2 stopped because of side effects, and 4 did not comply with the regimen. In conclusion, pindolol appears to be safe and effective as initial treatment for vasovagal syncope.

引用

页码：786 / 790

页数：5

共 18 条

[1] THE USEFULNESS OF HEAD-UP TILT TESTING AND HEMODYNAMIC INVESTIGATIONS IN THE WORKUP OF SYNCOPE OF UNKNOWN ORIGIN [J].