METAL-ION CHELATION CHROMATOGRAPHY ON SILICA-IMMOBILIZED 8-HYDROXYQUINOLINE

A chromatographically useful packing is prepared by immobilizing 8-hydroxyquinoline on Porasil. This material, whose capacity is about 50 μequiv/g, behaves with an efficiency of about 0.2-0.5 mm/theoretical plate but is capable of separating such similar metal ions as Co-Ni, Cd-Pb-Zn, La-Gd-Yb at trace levels employing both isocratic and continuous gradient elution. On a fundamental level, the relationship between solution chelate stability and chromatographic behavior is described. © 1979, American Chemical Society. All rights reserved.