RANDOMIZED TRIAL OF THORACIC IRRADIATION PLUS COMBINATION CHEMOTHERAPY FOR UNRESECTABLE ADENOCARCINOMA AND LARGE CELL-CARCINOMA OF THE LUNG

被引：24

作者：

EAGAN, RT

LEE, RE

FRYTAK, S

FLEMING, TR

CREGAN, ET

INGLE, JN

KVOLS, LK

机构：

[1] MAYO CLIN & MAYO FDN,DIV THERAPEUT RADIOL,ROCHESTER,MN 55901

[2] MAYO CLIN & MAYO FDN,CTR CANC STAT,ROCHESTER,MN 55901

来源：

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | 1979年 / 5卷 / 08期

关键词：

Chemotherapy; Combined modality therapy; Lung cancer; Radiation therapy;

D O I：

10.1016/0360-3016(79)90678-3

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Sixty-eight evaluable patients with unresectable adenocarcinoma and large cell carcinoma of the lung were treated on a prospective randomized trial comparing thoracic radiation therapy (TRT) plus combination chemotherapy with either cyclophosphamide, Adriamycin and cis-platinum (CAP) or cyclophosphamide, Adriamycin (same dosages) and DTIC (CAD), 34 on each arm. Patients treated with TRT plus CAP had a better overall regression rate (59% vs 47%) and a statistically significant superiority in time to disease progression (147 days vs 303 days) and survival (217 days vs 504 days). © 1979.

引用

页码：1401 / 1405

页数：5

共 17 条

[1]

ABRAMSON N, 1970, RADIOLOGY, V96, P627

[2]

CARR DT, 1972, CANCER, V29, P375, DOI 10.1002/1097-0142(197202)29:2<375::AID-CNCR2820290218>3.0.CO

[3]

2-H

[4]

EAGAN RT, 1977, CANCER TREAT REP, V61, P93

[5]

EAGAN RT, 1977, CANCER TREAT REP, V61, P1339

[6]

GRISWOLD DP, 1973, P AM ASSOC CANC RES, V14, P15

[7]

HANSEN HH, 1972, CANCER, V30, P315, DOI 10.1002/1097-0142(197208)30:2<315::AID-CNCR2820300202>3.0.CO

[8]

2-E

[9]

PETROVICH Z, 1977, CANCER, V40, P72, DOI 10.1002/1097-0142(197707)40:1<72::AID-CNCR2820400114>3.0.CO

[10]

2-Q

← 1 2 →