NO SENSORY NEUROPATHY DURING PYRIDOXINE TREATMENT IN HOMOCYSTINURIA

被引:17
作者
MPOFU, C
ALANI, SM
WHITEHOUSE, C
FOWLER, B
WRAITH, JE
机构
[1] ROYAL MANCHESTER CHILDRENS HOSP,WILLINK BIOCHEM GENET UNIT,MANCHESTER M27 1HA,LANCS,ENGLAND
[2] ROYAL MANCHESTER CHILDRENS HOSP,DEPT NEUROPHYSIOL,MANCHESTER M27 1HA,LANCS,ENGLAND
关键词
D O I
10.1136/adc.66.9.1081
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Seventeen patients with cystathionine synthase deficiency homocystinuria were examined clinically and neurophysiologically for evidence of sensory neuropathy. All had received high dose pyridoxine (vitamin B-6) for many years. Absence of neurological disturbance in all cases suggests long term treatment with pyridoxine in the dosages used in homocystinuric patients is not harmful.
引用
收藏
页码:1081 / 1082
页数:2
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