CONGENITAL INSENSITIVITY TO PAIN - A 20-YEAR FOLLOW-UP

被引：10

作者：

LARNER, AJ

MOSS, J

ROSSI, ML

ANDERSON, M

机构：

[1] MIDLAND CTR NEUROSURG & NEUROL,SMETHWICK B67 7JX,W MIDLANDS,ENGLAND

[2] CHARING CROSS HOSP,LONDON W6 8RF,ENGLAND

[3] UNIV CAMBRIDGE,DEPT HISTOPATHOL,CAMBRIDGE CB2 3DY,ENGLAND

[4] UNIV CAMBRIDGE,DEPT FORENS MED,CAMBRIDGE CB2 3DY,ENGLAND

来源：

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY | 1994年 / 57卷 / 08期

关键词：

D O I：

10.1136/jnnp.57.8.973

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The exact nosological status of ''congenital insensitivity to pain'' remains in doubt. Possible pathological correlates of this clinical syndrome include sensory neuropathy, central lesions at the level of the reticular formation or dorsal horn of the spinal cord, or a central indifference to, or asymbolia for, pain. The reassessment of two members of a kindred previously reported more than 20 years ago as having congenital insensitivity to pain indicated that they in fact had an inherited sensory and autonomic neuropathy. Prolonged follow up and morphometric analysis of sequential nerve biopsies may be necessary to definitively establish this diagnosis.

引用

页码：973 / 974

页数：2

共 7 条

[1] HEREDITARY SENSORY NEUROPATHY WITH NEUROTROPHIC KERATITIS - DESCRIPTION OF AN AUTOSOMAL RECESSIVE DISORDER WITH A SELECTIVE REDUCTION OF SMALL MYELINATED NERVE-FIBERS AND A DISCUSSION OF THE CLASSIFICATION OF THE HEREDITARY SENSORY NEUROPATHIES [J].