REGIOSELECTIVE N-ALKYLATION IN 5-FLUOROURACIL

被引：17

作者：

GACEK, M

UNDHEIM, K

机构：

来源：

ACTA CHEMICA SCANDINAVICA SERIES B-ORGANIC CHEMISTRY AND BIOCHEMISTRY | 1979年 / 33卷 / 07期

关键词：

D O I：

10.3891/acta.chem.scand.33b-0515

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

5-Fluorouracil [an antineoplastic drug] was alkylated selectively on N-1 via its 4-methylthio derivative. Similarly N-3 alkylation was achieved via the 2-methylthio derivative of 5-fluorouracil.

引用

页码：515 / 518

页数：4

共 13 条

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