AN IMPROVED SYNTHESIS OF THE TAXOL SIDE-CHAIN AND OF RP-56976

被引：216

作者：

DENIS, JN ^{[1
]}

CORREA, A ^{[1
]}

GREENE, AE ^{[1
]}

机构：

[1] UNIV JOSEPH FOURIER,LEDSS,BAT 52,F-38041 GRENOBLE,FRANCE

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1990年 / 55卷 / 06期

关键词：

D O I：

10.1021/jo00293a052

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Efforts directed toward the total synthesis of taxol, a highly promising anticancer natural product,1 continue unabated.2 In most, if not all, of the numerous approaches recorded to date it would appear that an esterification of the C-13 hydroxyl function of an appropriate taxol precursor with the enantiomerically pure (suitably protected) taxol side chain will ultimately be required to obtain taxol efficiently3. © 1990, American Chemical Society. All rights reserved.

引用

页码：1957 / 1959

页数：3

共 22 条

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