PREVENTION OF PENICILLIN-INDUCED LYSIS OF STAPHYLOCOCCUS-AUREUS BY CELLULAR LIPOTEICHOIC ACID

被引：23

作者：

SUGINAKA, H ^{[1
]}

SHIMATANI, M ^{[1
]}

OGAWA, M ^{[1
]}

KOTANI, S ^{[1
]}

机构：

[1] OSAKA UNIV,SCH MED,DEPT SURG 2,KITA KU,OSAKA 530,JAPAN

来源：

JOURNAL OF ANTIBIOTICS | 1979年 / 32卷 / 01期

关键词：

D O I：

10.7164/antibiotics.32.73

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The lysis of Staphylococcus aureus FDA 209P induced by benzylpenicillin was completely inhibited by cellular lipoteichoic acid isolated from an homologous organism. The cells prevented from penicillin-induced lysis were in static state and did not lose viability. The lipoteichoic acid inhibited either extracellular autolysin activity in culture supernatant or autolysis of whole cells in exponential phase of S. aureus. These results indicate that the prevention of penicillin-induced lysis of S. aureus by the lipoteichoic acid was brought about by the inhibition of autolytic activity of the organism. © 1979, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.

引用

页码：73 / 77

页数：5

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