MOVEMENT OF PROTEINS THROUGH THE GOLGI STACK - A MOLECULAR DISSECTION OF VESICULAR TRANSPORT

被引：143

作者：

ROTHMAN, JE ^{[1
]}

ORCI, L ^{[1
]}

机构：

[1] UNIV GENEVA,SCH MED,DEPT MORPHOL,CH-1211 GENEVA 4,SWITZERLAND

来源：

FASEB JOURNAL | 1990年 / 4卷 / 05期

关键词：

clathrin; coated vesicle; glycoprotein; Golgi cisternae;

D O I：

10.1096/fasebj.4.5.2407590

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A combination of cell-free biochemical and morphological studies has revealed that a coated bud-coated vesicle transport system shuttles newly synthesized proteins through the successive processing compartments of the Golgi apparatus. These Golgi-coated vesicles operate in a manner formally analogous to the clathrin-coated, pit-coated vesicle system responsible for receptor-mediated endocytosis; however Golgi-coated vesicles do not contain clathrin.

引用

页码：1460 / 1468

页数：9

共 41 条

[1] Role of the coated endocytic vesicle in the uptake of receptor-bound low density lipoprotein in human fibroblasts
ANDERSON, RGW
BROWN, MS
GOLDSTEIN, JL
[J]. CELL, 1977, 10 (03) : 351 - 364
[2] THE GTP-BINDING PROTEIN YPT1 IS REQUIRED FOR TRANSPORT INVITRO - THE GOLGI-APPARATUS IS DEFECTIVE IN YPT1 MUTANTS
BACON, RA
SALMINEN, A
RUOHOLA, H
NOVICK, P
FERRONOVICK, S
[J]. JOURNAL OF CELL BIOLOGY, 1989, 109 (03) : 1015 - 1022
[3] RECONSTITUTION OF SEC GENE PRODUCT-DEPENDENT INTERCOMPARTMENTAL PROTEIN-TRANSPORT
BAKER, D
HICKE, L
REXACH, M
SCHLEYER, M
SCHEKMAN, R
[J]. CELL, 1988, 54 (03) : 335 - 344
[4] BAKER D, IN PRESS GTP BINDING
[5] RECONSTITUTION OF THE TRANSPORT OF PROTEIN BETWEEN SUCCESSIVE COMPARTMENTS OF THE GOLGI MEASURED BY THE COUPLED INCORPORATION OF N-ACETYLGLUCOSAMINE
BALCH, WE
DUNPHY, WG
BRAELL, WA
ROTHMAN, JE
[J]. CELL, 1984, 39 (02) : 405 - 416
[6] SEQUENTIAL INTERMEDIATES IN THE PATHWAY OF INTERCOMPARTMENTAL TRANSPORT IN A CELL-FREE SYSTEM
BALCH, WE
GLICK, BS
ROTHMAN, JE
[J]. CELL, 1984, 39 (03) : 525 - 536
[7] VESICULAR TRANSPORT BETWEEN THE ENDOPLASMIC-RETICULUM AND THE GOLGI STACK REQUIRES THE NEM-SENSITIVE FUSION PROTEIN
BECKERS, CJM
BLOCK, MR
GLICK, BS
ROTHMAN, JE
BALCH, WE
[J]. NATURE, 1989, 339 (6223) : 397 - 398
[8] SEMI-INTACT CELLS PERMEABLE TO MACROMOLECULES - USE IN RECONSTITUTION OF PROTEIN-TRANSPORT FROM THE ENDOPLASMIC-RETICULUM TO THE GOLGI-COMPLEX
BECKERS, CJM
KELLER, DS
BALCH, WE
[J]. CELL, 1987, 50 (04) : 523 - 534
[9] FLUORIDE COMPLEXES OF ALUMINUM OR BERYLLIUM ACT ON G-PROTEINS AS REVERSIBLY BOUND ANALOGS OF THE GAMMA-PHOSPHATE OF GTP
BIGAY, J
DETERRE, P
PFISTER, C
CHABRE, M
[J]. EMBO JOURNAL, 1987, 6 (10) : 2907 - 2913
[10] PURIFICATION OF AN N-ETHYLMALEIMIDE-SENSITIVE PROTEIN CATALYZING VESICULAR TRANSPORT
BLOCK, MR
GLICK, BS
WILCOX, CA
WIELAND, FT
ROTHMAN, JE
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (21) : 7852 - 7856

← 1 2 3 4 5 →