12-LIPOXYGENASE ACTIVITY IN THE RED MARINE ALGA GRACILARIOPSIS-LEMANEIFORMIS

被引：17

作者：

MOGHADDAM, MF

GERWICK, WH

机构：

[1] College of Pharmacy, Oregon State University, Corvallis

来源：

PHYTOCHEMISTRY | 1990年 / 29卷 / 08期

关键词：

12-HETE; 12-hydroxyicosatetraenoic acid; 12-lipoxygenase; algae; Gracilariopsis lemaneiformis; icosanoids; Rhodophyta;

D O I：

10.1016/0031-9422(90)85166-D

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The temperate red alga Gracilariopsis lemaneiformis is a rich source of polyunsaturated fatty acids that are regio-specifically oxidized at C-12. In this in vitro study, we demonstrate the existence of a highly active lipoxygenase-type activity in Gracilariopsis. GC-MS of the methyl ester, trimethylsilyl ether derivatives of the crude reaction mixture identified the production of 12-hydroxyicosatetraenoic acid, a 12-lipoxygenase product previously isolated from this alga. This is the first report of 12-lipoxygenase-type activity from the plant kingdom. © 1990.

引用

页码：2457 / 2459

页数：3

共 16 条

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