IMMUNE INTERFERON PRODUCED INVITRO AS A QUANTITATIVE INDICATOR OF CELL-MEDIATED-IMMUNITY

被引：15

作者：

ITO, Y ^{[1
]}

NISHIYAMA, Y ^{[1
]}

SHIMOKATA, K ^{[1
]}

TAKEYAMA, H ^{[1
]}

KUNII, A ^{[1
]}

机构：

[1] NAGOYA UNIV,DEPT INTERNAL MED 1,NAGOYA,AICHI 464,JAPAN

来源：

MICROBIOLOGY AND IMMUNOLOGY | 1979年 / 23卷 / 12期

关键词：

D O I：

10.1111/j.1348-0421.1979.tb00549.x

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The present study was constructed to provide some information on the possibility of utilizing immune interferon as a quantitative indicator of cell-mediated immunity and to clarify some of the nature of immune interferon-producing cells (IIPC). When spleen cells derived from L cell-sensitized mice were co-cultivated with L cells, interferon appeared in the culture fluid. It was shown by additional experiments that the cells responsible for immune interferon production in this system were T-lymphocytes assisted by macrophages. The pattern of kinetics of immune interferon production in vitro was similar to that of migration inhibitory factor or T cell-mediated cytotoxicity. © 1979, Center For Academic Publications Japan. All rights reserved.

引用

页码：1169 / 1177

页数：9

共 25 条

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