EFFECTS OF APOMORPHINE AND L-DOPA ON THE PARKINSONIAN BLADDER

被引：86

作者：

ARANDA, B

CRAMER, P

机构：

[1] Department of Rehabilitation, Centre Hospitaller, Gonesse

来源：

NEUROUROLOGY AND URODYNAMICS | 1993年 / 12卷 / 03期

关键词：

HYPERREFLEXIC BLADDER; HYPOREFLEXIC BLADDER; PARKINSONS DISEASE; DOPAMINE AGONIST;

D O I：

10.1002/nau.1930120302

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Neurogenic bladder frequently occurs in Parkinson's disease. Detrusor hyperreflexia is a consequence of nigrostriatal dopamine depletion, whereas the cause of hyporeflexia remains unclear. We compared the results of cystometry and urethral profilometry with and without apomorphine (and L dopa) in 12 idiopathic parkinsonians with urinary disorders free of dopaminergic treatment. Whereas hyperreflexic patients improved with apomorphine, and to a lesser extent with L dopa, these drugs had no effect on hyporeflexic patients. These results confirm the role of dopaminergic lesions in the occurrence of bladder hyperreflexia and the possible implication of nondopaminergic lesions in the occurrence of hyporeflexia.

引用

页码：203 / 209

页数：7