INVIVO STIMULATION OF A CHOLINERGIC SYNAPSE OF THE CHICK CILIARY GANGLION INDUCES A REDUCTION IN THE NUMBER OF DENSE CORE VESICLES

被引：17

作者：

PHILIPPE, E ^{[1
]}

TREMBLAY, JP ^{[1
]}

机构：

[1] HOP ENFANT JESUS, CTR NEUROBIOL, QUEBEC CITY G1J 5B3, QUEBEC, CANADA

来源：

NEUROSCIENCE LETTERS | 1981年 / 24卷 / 03期

关键词：

D O I：

10.1016/0304-3940(81)90176-2

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The Edinger-Westphal nucleus of young chicks (1 day old) was stimulated in vivo with a monopolar electrode at 100 Hz during 15, 60 or 225 min. This stimulation produced quantitative morphological changes in the cholinergic synaptic terminal located in the ciliary ganglion. As previously observed at the neuromuscular junction, there is a significant reduction of the numerical density on area (NA) of the clear vesicles and an increase in the NA of the coated vesicles. A significant reduction of the NA of the dense core vesicles (DCV) was also observed. Apparently, these DCVs contain a peptide neurotransmitter and their reduced NA is due to exocytosis which would liberate the peptide during synaptic activity.

引用

页码：307 / 312

页数：6

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