METALLOTHIONEIN REACTS WITH FE2+ AND NO TO FORM PRODUCTS WITH A G=2.039 ESR SIGNAL

被引：56

作者：

KENNEDY, MC

GAN, T

ANTHOLINE, WE

PETERING, DH

机构：

[1] UNIV WISCONSIN, DEPT CHEM, MILWAUKEE, WI 53201 USA

[2] MED COLL WISCONSIN, NATL BIOMED ESR CTR, MILWAUKEE, WI 53226 USA

来源：

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1993年 / 196卷 / 02期

关键词：

D O I：

10.1006/bbrc.1993.2296

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The interaction of metallothionein, Fe2+, and nitric oxide has been examined by electron spin resonance spectroscopy. When either apoMT 2 or Zn-MT 2 from rabbit liver was mixed with Fe2+ and NO, paramagnetic products with g values of 2.013 and 2.039 were found. These are characteristic of iron nitrosyl thiolates with stoichiometry, Fe(NO)2(SR)2. This product was not generated when beef heart mitochondrial aconitase was used as the source of iron. © 1993 Academic Press, Inc.

引用

页码：632 / 635

页数：4

共 23 条

[1]

BUHLER RHO, 1989, METALLOTHIONEIN, P211

[2] NITROSYL COMPLEXES OF IRON SULFUR CLUSTERS [J].