ULTRASTRUCTURAL AND ELECTRO-PHYSIOLOGICAL FEATURES OF MENINGIOMA WHORLS IN TISSUE-CULTURE

被引:5
作者
BLACK, PM
LISZCZAK, T
KORNBLITH, PL
机构
[1] Neurosurgical Service, Massachusetts General Hospital, Boston, 02114, MA
关键词
Brain neoplasms; Cells; cultured; Intercellular junctions; Meningioma; Tissue culture;
D O I
10.1007/BF00684801
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Cultured cells derived from a psammomatous meningioma were induced to from whorls in vitro by deprivation of nutrients. The ultrastructural features of desmosomes and junctional complexes were similar to sections from the surgical specimen; also prominent were 9-10 nm cytoplasmic filaments. Microelectrode recording of whorled cells showed a larger resting membrane potential than that of similar isolated meningioma cells in culture. Whorl formation seen in this tumor may be a result of relative nutritional deprivation and the need for metabolic cooperation among tumor cells. © 1979 Springer-Verlag.
引用
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页码:33 / 38
页数:6
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