SEPARATION OF NATURAL POLYUNSATURATED FATTY-ACIDS BY MEANS OF IODOLACTONIZATION

被引：14

作者：

GAIDAY, NV ^{[1
]}

IMBS, AB ^{[1
]}

KUKLEV, DV ^{[1
]}

LATYSHEV, NA ^{[1
]}

机构：

[1] ACAD SCI USSR,INST MARINE BIOL,FAR E BRANCH,VLADIVOSTOK 690032,USSR

来源：

JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY | 1991年 / 68卷 / 04期

关键词：

ARACHIDONIC ACID; IODOLACTONIZATION; SEPARATION OF FATTY ACIDS;

D O I：

10.1007/BF02657614

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Conditions of the iodolactonization reaction (IL-reaction) were optimized as a method for separation of natural polyunsaturated fatty acids. The effects of the solvent, temperature and the ratio of components of the iodizing complex KI/I2 upon the rate of the synthesis of several iodolactones (ILs) in the IL-reaction are described. It was shown that the rate of formation of gamma-ILs was significantly higher than that for delta-ILs. This offers opportunity for obtaining pure docosahexaenoic acid (DHA) from fatty acid (FA) concentrates. The possibility for selective reduction of delta-ILs in the presence of gamma-ILs to yield pure arachidonic acid (AA) or eicosapentaenoic acid (EPA) or fatty acid concentrates has been demonstrated. Preparation of pure AA from a mixture of AA, DHA and other FAs by the IL-reaction without chromatographic procedures is described.

引用

页码：230 / 233

页数：4

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