INTERFERENCE OF CEFOXITIN IN THE CREATININE ESTIMATION AND ITS CLINICAL RELEVANCE

被引：33

作者：

DURHAM, SR

BIGNELL, AHC

WISE, R

机构：

[1] DUDLEY RD HOSP,DEPT MED MICROBIOL,BIRMINGHAM B18 7QH,W MIDLANDS,ENGLAND

[2] DUDLEY RD HOSP,DEPT CLIN CHEM,BIRMINGHAM B18 7QH,W MIDLANDS,ENGLAND

来源：

JOURNAL OF CLINICAL PATHOLOGY | 1979年 / 32卷 / 11期

关键词：

D O I：

10.1136/jcp.32.11.1148

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

Serum creatinine and creatinine clearance were measured in 10 healthy volunteers before and after an intravenous injection of 2 g cefoxitin sodium. Results were compared with in vitro work which demonstrated a positive interference by cefoxitin in the Jaffe reaction, the routine laboratory method of creatinine measurement. The serum creatinine estimation should be delayed until at least 2 hours after cefoxitin administration. The creatinine clearance may appear to be falsely high.

引用

页码：1148 / 1151

页数：4

共 17 条

[1]

ANNINO JS, 1959, AM J CLIN PATHOL, V31, P155

[2] JAFFE REACTION - IDENTIFICATION OF COLORED SPECIES [J].