BILATERAL REORGANIZATION OF MOSSY FIBERS IN THE RAT HIPPOCAMPUS AFTER A UNILATERAL INTRACEREBROVENTRICULAR KAINIC ACID INJECTION

被引：51

作者：

SUNDSTROM, LE ^{[1
]}

MITCHELL, J ^{[1
]}

WHEAL, HV ^{[1
]}

机构：

[1] UNIV SOUTHAMPTON,DEPT HUMAN MORPHOL,SOUTHAMPTON SO9 3TU,HANTS,ENGLAND

来源：

BRAIN RESEARCH | 1993年 / 609卷 / 1-2期

关键词：

EPILEPSY; HIPPOCAMPUS; KAINIC ACID; PLASTICITY; SPROUTING;

D O I：

10.1016/0006-8993(93)90890-Y

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

One month after a unilateral intracerebroventricular injection of the neurotoxin kainic acid (KA) a prominent band of zinc-containing Timm's-stained terminals is present in the inner molecular layer of the ipsilateral dentate gyrus. At 3 months, mossy fibre reorganisation is also seen in the contralateral inner molecular layer of the dentate gyrus and in the infrapyiramidal band in the contralateral CA3. The relationship of this reactive plasticity to the CA3 lesion is discussed.

引用

页码：321 / 326

页数：6

共 36 条

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