A NOVEL SYNTHETIC APPROACH TO ALPHA-ALKYLIDENE-BETA-LACTAMS

被引：16

作者：

ALCAIDE, B

PLUMET, J

RODRIGUEZLOPEZ, J

SANCHEZCANTALEJO, YM

机构：

[1] Departamento de Química Orgánica, Facultad de Química, Universidad Complutense, 28040 Madrid, Ciudad Universitaria

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 17期

关键词：

D O I：

10.1016/S0040-4039(00)97398-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple strategy for the synthesis of various α-alkylidene-β-lactams 4 based upon the condensation between lithium enolates of 3-(N,N-dialkylamino)esters and imines followed by straightforward deamination of the resulting 3-aminoalkyl-β-lactams 3 is outlined. The synthesis of α-alkylidene-β-formyl-β-lactams is a particularly significant feature of this work. © 1990.

引用

页码：2493 / 2496

页数：4

共 33 条

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