COMPOUNDS WITH BRIDGEHEAD NITROGEN .68. NMR-SPECTRA AND STEREOCHEMISTRY OF PERHYDROPYRIDO [1,2-C][1,3]OXAZINES

被引：8

作者：

CRABB, TA

INGATE, ST

NEVELL, TG

机构：

[1] Department of Chemistry, Portsmouth Polytechnic, Portsmouth, Hampshire

来源：

MAGNETIC RESONANCE IN CHEMISTRY | 1992年 / 30卷 / 02期

关键词：

PERHYDROPYRIDO[1,2-C][1,3]OXAZINES; H-1 AND C-13 NMR;

D O I：

10.1002/mrc.1260300207

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Low-temperature C-13 NMR spectroscopy shows perhydropyrido[1,2-c][1,3]oxazine to adopt a conformational equilibrium in CD2Cl2-CFCl3 solution containing 98% trans fused conformer in equilibrium with 2% O-outside-cis fused conformer at 203 K. A similar equilibrium position is adopted by the trans-(H-4,H-4a)-4-methylperhydropyrido[1,2-c][1,3]oxazine, whereas the C-4 epimer adopts exclusively the trans fused conformation.

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页码：129 / 132

页数：4

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