CONFORMATIONAL-ANALYSIS OF DELTA-LACTAMS

被引：19

作者：

BOUDREAULT, N

BALL, RG

BAYLY, C

BERNSTEIN, MA

LEBLANC, Y

机构：

[1] MERCK FROSST CTR THERAPEUT RES,POINTE CLAIRE H9R 4P8,PQ,CANADA

[2] MERCK & CO INC,RAHWAY,NJ 07065

来源：

TETRAHEDRON | 1994年 / 50卷 / 27期

关键词：

D O I：

10.1016/S0040-4020(01)85279-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

delta-lactams substituted at C-5 by an oxygen atom exist, in solution principally, in the axial conformation. This axial preferred form is also present in the solid state.

引用

页码：7947 / 7956

页数：10

共 23 条

[1]

ALLINGER NL, 1980, ISRAEL J CHEM, V20, P51

[2] AXIAL EQUATORIAL PROPORTIONS FOR 2-SUBSTITUTED CYCLOHEXANONES [J].

BASSO, EA ;

KAISER, C ;

RITTNER, R ;

LAMBERT, JB .

JOURNAL OF ORGANIC CHEMISTRY, 1993, 58 (27) :7865-7869

[3] DETERMINATION OF THE GAUCHE EFFECT OF 3-ACETAMIDO-PIPERIDINE AND 3-ACETOXY-PIPERIDINE AND 3-ACETOXYTETRAHYDROPYRAN BY H-1-NMR SPECTROSCOPY [J].

BERNET, B ;

PIANTINI, U ;

VASELLA, A .

CARBOHYDRATE RESEARCH, 1990, 204 :11-25

[4]

Delaude, 1986, ALKALOIDS, V27, P269

[5] SYNTHESIS OF 2-AMINO C-GLUCOSIDES AND 2-AMINO C-GLUCOSIDE SPIROKETALS [J].

GRONDIN, R ;

LEBLANC, Y ;

HOOGSTEEN, K .

TETRAHEDRON LETTERS, 1991, 32 (38) :5021-5024

[6]

HAASNOOT CAG, 1980, B SOC CHIM BELG, V89, P125

[7] THE RELATIONSHIP BETWEEN PROTON-PROTON NMR COUPLING-CONSTANTS AND SUBSTITUENT ELECTRONEGATIVITIES .1. AN EMPIRICAL GENERALIZATION OF THE KARPLUS EQUATION [J].

HAASNOOT, CAG ;

DELEEUW, FAAM ;

ALTONA, C .

TETRAHEDRON, 1980, 36 (19) :2783-2792

[8]

HERDEIS C, 1986, SYNTHESIS-STUTTGART, P232

[9] SUBSTITUTED GAMMA-LACTONES WITH VICINAL HYDROGEN-ATOMS - CONFORMATIONAL STUDY BY MM2 CALCULATIONS AND COUPLING-CONSTANT ANALYSIS [J].

JAIME, C ;

SEGURA, C ;

DINARES, I ;

FONT, J .

JOURNAL OF ORGANIC CHEMISTRY, 1993, 58 (01) :154-158

[10]

KECK GE, 1979, TETRAHEDRON LETT, P1185

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