LOSS OF ACETYLCHOLINESTERASE ACTIVITY IN HUMAN ERYTHROCYTES TREATED WITH CEPHALOTHIN

被引：8

作者：

HERZ, F

KAPLAN, E

SEVDALIAN, DA

机构：

[1] Departments of Pediatrics, Sinai Hospital of Baltimore, The Johns Hopkins University School of Medicine, Baltimore, MD

来源：

ACTA HAEMATOLOGICA | 1969年 / 41卷 / 02期

关键词：

D O I：

10.1159/000208836

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Treatment of human erythrocytes with cephalothin caused irreversible inactivation of the surface located acetylcholinesterase (ACHE). The effect on the enzyme was dependent on concentration, time and temperature. ACHE inactivation was prevented by plasma but not by agglutinating the red cells with blood-group specific antibodies. The intracellularly located glucose-6-phosphate dehydrogenase was not affected by cephalothin. Cephaloridine and cephaloglycin had no effect on ACHE. © 1969 S. Karger AG, Basel.

引用

页码：94 / +

页数：1

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