HUMAN PANCREATIC AMYLASE POLYMORPHISM - FORMAL GENETICS AND POPULATION-GENETICS

被引：9

作者：

KOMPF, J

SIEBERT, G

RITTER, H

机构：

[1] Institut für Anthropologie und Humangenetik der Universität Tübingen, Tübingen, D-7400

来源：

HUMAN GENETICS | 1979年 / 51卷 / 02期

关键词：

D O I：

10.1007/BF00287179

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The genetically determined polymorphism of human pancreatic amylase (E.C. 3.2.1.1), AMY2, is demonstrated in serum specimens by agarose gel electrophoresis. We, investigated 325 mother-child pairs and 2594 unrelated individuals from southwestern Germany. This study confirms the formal hypothesis of two common alleles AMY21, AMY22and possibly two rare alleles AMY23, AMY24at an autosomal locus AMY2. The frequency of the AMY21allele, was calculated as 0.951; AMY23and AMY24seem to have a frequency of 0.001 in this sample. © 1979 Springer-Verlag.

引用

页码：217 / 220

页数：4