COEXISTENCE OF CRF PEPTIDE AND OXYTOCIN MESSENGER-RNA IN THE PARAVENTRICULAR NUCLEUS

被引：11

作者：

PRETEL, S

PIEKUT, DT

机构：

[1] The Neuroendocrine Unit, University of Rochester, School of Medicine and Dentistry, Rochester, NY 14642

来源：

PEPTIDES | 1990年 / 11卷 / 03期

关键词：

Double-label; Immunocytochemistry; mRNA; Paraventricular nucleus;

D O I：

10.1016/0196-9781(90)90068-G

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Several studies have reported coexistences of peptides in parvocellular neurons of the paraventricular nucleus (PVN). However, the coexistence of peptides in the magnocellular PVN is less clear. Controversy exists in particular about the coexistence of corticotropin-releasing factor (CRF) and oxytocin (OX). Although these peptides are present in distinct areas of the PVN, some overlap may exist. This study investigated a potential coexistence of OX and CRF in magno- and parvocellular PVN. The data demonstrate with clarity that neurons containing both the mRNA for OX and the peptide CRF are present in subpopulations of magnocellular and parvocellular neurons of the PVN. © 1990.

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页码：621 / 624

页数：4

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